Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 9 de 9
Filtrar
Más filtros










Base de datos
Intervalo de año de publicación
1.
Arch Environ Occup Health ; 78(7-8): 379-388, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37909318

RESUMEN

INTRODUCTION: This study examined emergency physicians across the country in terms of Impostor Phenomenon (IP) and Burnout Syndrome (BoS). We aimed to evaluate the possible relationship between IP and BoS and determine which demographic characteristics pose a risk for IP and BoS. METHODS: This quantitative cross-sectional study consists of Clance Impostor Phenomenon Scale (CIPS) and Maslach Burnout Inventory (MBI) which were filled out online by the participants. A total of 389 volunteers participated in the study. RESULTS: The median age of participants was 30 years (Q1-Q3=27-35) and 57.3% (223) of them were male. The frequency of significant/intense IP was higher in women (28.9%) than in men (17%) (p=0.020). High emotional exhaustion and low personal accomplishment were more common in women than in men (71.7% vs 60.6% and 50% vs 31%, respectively). The median age of participants classified as none to mild IP was 34 years. It was 28 years in significant/intense IP. It was detected that the severity of IP increased as the participants got younger (p<0.001). Significant/intense IP was most common in residents (29%). The residents also had the highest frequency of depersonalization (73.5%). The frequency of moderate to intense IP was the least in participants who worked at a university hospital (74.6%). CONCLUSION: The results of this study indicated that IP and BoS are more common in residency. The increased frequency of IP and BoS in young female physicians may be attributed to hierarchical working arrangements and worry about academic performance. Experienced physicians with high levels of academic self-consciousness exhibited a low frequency of IP. Additionally, this study identified a moderate correlation between IP and BoS.


Asunto(s)
Agotamiento Profesional , Médicos , Humanos , Masculino , Femenino , Adulto , Estudios Transversales , Agotamiento Profesional/epidemiología , Agotamiento Profesional/psicología , Encuestas y Cuestionarios , Agotamiento Psicológico , Médicos/psicología
2.
Heliyon ; 9(9): e19982, 2023 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-37809508

RESUMEN

Objective: End tidal carbon dioxide (EtCO2) is measured to confirm the placement of an endotracheal tube and evaluate the efficacy of cardiopulmonary resuscitation (CPR), and as an assistive tool for terminating CPR. However, there are no highly accurate or definitive recommendations for its use when deciding on the termination of CPR. We aimed to merge EtCO2 values with existing termination of resuscitation (TOR) rules to obtain a more accurate combination for terminating resuscitation. Methods: This observational, prospective study included non-traumatic adult patients who were admitted to a tertiary university hospital Emergency Medicine Department due to cardiac arrest. EtCO2 cutoff values (at 5, 10, and 20 min) were integrated into currently used TOR parameters (arrest was not witnessed, no bystander CPR was provided, no return of spontaneous circulation (ROSC) after full advanced life support care in the field, and no shock was delivered) and the extended TOR rule was created. These extended TOR rules were compared at three different times (5, 10, and 20 min) for specificity and positive predictive value for ROSC. Results: We included a total of 86 cases. The cutoff value of EtCO2 from ROC analysis was 19.5, 23.5, and 20.5 mmHg at 5, 10, and 20 min, respectively. "The extended TOR rule created with the 20-min EtCO2 cutoff (20.5 mmHg) was the most accurate in detecting ROSC (-) patients. The specificity was 100% (95% CI 63.1-100.0) sensitivity was 20.0% (95% CI 9.1-35.7), positive predictive value was 100% and negative predictive value was 20.0% (95% CI 17.6-22.6) for ROSC (-) patients. The parameters of this rule were as follows: arrest was not witnessed, no bystander CPR was provided, no ROSC after full advanced life support care in the field, no shock was delivered, and EtCO2 value at 20 min of resuscitation <20.5 mmHg. Conclusions: Integration of EtCO2 values into the classically used TOR criteria increases the specificity to 100% without a significant decrease in sensitivity. These results need to be validated in larger groups before this rule is used clinically. EtCO2 seems to be a beneficial tool in establishing new TOR rules.

3.
Biomimetics (Basel) ; 8(2)2023 Apr 13.
Artículo en Inglés | MEDLINE | ID: mdl-37092407

RESUMEN

Cell transplants in therapeutic studies do not preserve their long-term function inside the donor body. In mesenchymal stem cell (MSC) transplants, transplanted cells disperse through the body and are prone to degradation by immune cells after the transplant process. Various strategies, such as usage of the immunosuppressive drugs to eliminate allograft rejection, are designed to increase the efficiency of cell therapy. Another strategy is the construction of biomimetic encapsulates using polymeric materials, which isolate stem cells and protect them from environmental effects. In this study, fibroblasts (L929) and MSCs were investigated for their improved viability and functionality once encapsulated inside the alginate microbeads under in vitro conditions for up to 12 days of incubation. Thus, uniform and injectable (<200 µm) cell-loaded microbeads were constructed by the electrostatically assisted spraying technique. Results showed that both L929 and MSCs cells continue their metabolic activity inside the microbeads during the incubation periods. Glucose consumption and lactic acid production levels of both cell lines were consistently observed. The released cell number on day 12 was found to be increased compared to day 0. Protein expression levels of both groups increased every day with the expected doubling rate. Hence, this strategy with a simple yet clever design to encapsulate either MSCs or L929 cells might outstand as a potential cell delivery platform for cell therapy-based tissue engineering.

4.
World J Gastroenterol ; 22(16): 4219-25, 2016 Apr 28.
Artículo en Inglés | MEDLINE | ID: mdl-27122672

RESUMEN

AIM: To determine the prognostic risk factors of gastrointestinal bleeding in emergency department cases. METHODS: The trial was a retrospective single-center study involving 600 patients over 18-years-old and carried out with approval by the Institutional Ethics Committee. Patient data included demographic characteristics, symptoms at admission, past medical history, vital signs, laboratory results, endoscopy and colonoscopy results, length of hospital stay, need of intensive care unit (ICU) admission, and mortality. Mortality rate was the principal endpoint of the study, while duration of hospital stay, required interventional treatment, and admission to the ICU were secondary endpoints. RESULTS: The mean age of patients was 61.92-years-old. Among the 600 total patients, 363 (60.5%) underwent upper gastrointestinal endoscopy and the most frequent diagnoses were duodenal ulcer (19.2%) and gastric ulcer (12.8%). One-hundred-and-fifteen (19.2%) patients required endoscopic treatment, 20 (3.3%) required surgical treatment, and 5 (0.8%) required angiographic embolization. The mean length of hospital stay was 5.21 ± 5.85 d. The mortality rate was 6.3%. The ICU admission rate was 5.3%. Patients with syncope, higher blood glucose levels, and coronary artery disease had significantly higher ICU admission rates (P = 0.029, P = 0.043, and P = 0.002, respectively). Patients with low thrombocyte levels, high creatinine, high international normalized ratio, and high serum transaminase levels had significantly longer hospital stay (P = 0.02, P = 0.001, P = 0.019, and P = 0.005, respectively). Patients who died had significantly higher serum blood urea nitrogen and creatinine levels (P = 0.016 and P = 0.038), and significantly lower mean blood pressure and oxygen saturation (P = 0.004 and P = 0.049). Malignancy and low Glasgow coma scale (GCS) were independent predictive factors of mortality. CONCLUSION: Prognostic factors for gastrointestinal bleeding in emergency room cases are malignancy, hypotension on admission, low GCS, and impaired kidney function.


Asunto(s)
Embolización Terapéutica , Servicio de Urgencia en Hospital , Hemorragia Gastrointestinal/terapia , Hemostasis Endoscópica , Adulto , Anciano , Anciano de 80 o más Años , Úlcera Duodenal/mortalidad , Úlcera Duodenal/terapia , Embolización Terapéutica/efectos adversos , Embolización Terapéutica/mortalidad , Endoscopía Gastrointestinal , Femenino , Hemorragia Gastrointestinal/diagnóstico , Hemorragia Gastrointestinal/mortalidad , Escala de Coma de Glasgow , Hemostasis Endoscópica/efectos adversos , Hemostasis Endoscópica/mortalidad , Mortalidad Hospitalaria , Humanos , Hipotensión/mortalidad , Hipotensión/fisiopatología , Unidades de Cuidados Intensivos , Enfermedades Renales/mortalidad , Enfermedades Renales/fisiopatología , Tiempo de Internación , Masculino , Persona de Mediana Edad , Neoplasias/mortalidad , Úlcera Péptica Hemorrágica/mortalidad , Úlcera Péptica Hemorrágica/terapia , Estudios Retrospectivos , Factores de Riesgo , Úlcera Gástrica/mortalidad , Úlcera Gástrica/terapia , Factores de Tiempo , Resultado del Tratamiento , Turquía , Adulto Joven
5.
Ulus Travma Acil Cerrahi Derg ; 21(4): 248-55, 2015 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-26374410

RESUMEN

BACKGROUND: This study aimed to evaluate injury patterns of patients admitted to the emergency department with gunshot wounds, results of imaging studies, treatment modalities, outcomes, mortality ratios, and complications. METHODS: A retrospective descriptive study was carried out including a total number of one hundred and forty-two patients admitted to Hacettepe University Emergency Department with gunshot injuries between January 1, 1999 and December 31, 2013. The Glasgow Coma Scale (GCS), Revised Trauma Score (RTS), Injury Severity Score (ISS), and the Trauma and Injury Severity Score (TRISS) probability of survival for penetrating trauma were calculated for all patients. RESULTS: Among the one hundred and forty-two patients in the study, one hundred and twenty-eight (90.1%) were male. Mean age was 36 years. On admission, the average GCS score was 13, mean RTS was 6.64, median ISS was 5 and median TRISS probability for survival was 99.4% for penetrating trauma. Fluid was detected in three (13%) patients in FAST, whereas intra-abdominal solid organ injury and bowel injury were detected in 11 (58%) patients in abdominal CT. The pneumothorax, hemothorax and lung injuries were detected in 10 (40%) patients, whereas hemothorax was detected only in one patient with thoracic injury by chest X-ray. Twenty four (16.9%) patients died; eighteen patients (75%) had isolated severe intracranial injuries, two (8.3%) had thoracic injuries with head and neck injuries, and four (16.7%) patients had intra-abdominal organ injuries (one with concomitant head injury). Ten patients were brought to the ED in cardiopulmonary arrest. In dead patients, GCS, RTS and TRISS were significantly lower, and ISS were significantly higher than in surviving patients. Twenty three (95.8%) patients were in critical injury level (ISS 25-75, actually ISS >50) in the exitus group. CONCLUSION: Mortality rates in gunshot wound patients with cranial injuries are very high. Spontaneous return is not seen in patients brought to the ED in arrest state. Bullets can cause internal organ injuries which can be greater than expected. In thoracoabdominal gunshot wound injuries, conventional X-ray and bedside FAST can be ineffective in detecting the whole extent of intrathoracic and intra-abdominal injuries. Thus, thoracic and abdominal CT should be planned early for hemodynamically stable patients in order to eliminate causes of fatality and make a timely and correct diagnosis. ISS, RTS and GCS are useful in predicting prognosis and mortality. Especially in patients with ISS scores >50, the mortality rate can be as high as 96%.


Asunto(s)
Heridas por Arma de Fuego/epidemiología , Traumatismos Abdominales/epidemiología , Adolescente , Adulto , Anciano , Traumatismos del Brazo/epidemiología , Traumatismos Craneocerebrales/epidemiología , Servicio de Urgencia en Hospital , Femenino , Escala de Coma de Glasgow , Humanos , Puntaje de Gravedad del Traumatismo , Traumatismos de la Pierna/epidemiología , Masculino , Persona de Mediana Edad , Radiografía , Estudios Retrospectivos , Traumatismos Torácicos/epidemiología , Turquía/epidemiología , Heridas por Arma de Fuego/diagnóstico por imagen , Heridas por Arma de Fuego/mortalidad , Heridas por Arma de Fuego/cirugía , Adulto Joven
6.
Am J Emerg Med ; 32(6): 660-4, 2014 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-24661780

RESUMEN

OBJECTIVES: High International Normalized Ratio (INR) level resulting from warfarin use increases the risk of gastrointestinal hemorrhages. We aimed to compare the efficacy of prothrombin complex concentrates (PCC) and fresh frozen plasma (FFP) at lowering the INR level, decreasing active hemorrhages visible by endoscopy, and shortening the length of stay at the emergency department (ED). METHOD: This study is a prospective cohort study of consecutive patents with gastrointestinal hemorrhages that received either PCC or FFP. With strict exclusion criteria, only patients over 18 years of age with a high INR level (>2.1) due to warfarin usage were included. RESULTS: A total of 40 patients (18 female) were included in the study, 20 each in the PCC and FFP groups. For the PCC group, the mean INR levels at the second and sixth hours were lower than those for the FFP group (second hour INR: 1.53 vs 4.50, P<.01, sixth hour INR: 1.52 vs 2.41, P<.01). Seven patients experienced active bleeding (Forrest 1) in the FFP group, whereas no patient experienced active bleeding in the PCC group based on the Forrest classification (35% vs 0%, P<.01), and only 3 patients in the FFP group underwent invasive/surgical treatment (15% vs 0%, P<.01). The ED length of stay was lower for the PCC group (1.62 days vs 3.46 days, P<.01). CONCLUSION: For patients experiencing a gastrointestinal hemorrhage, INR levels were reversed more quickly, there was less active bleeding on endoscopy, and the ED length of stay was lower in the PCC group than in the FFP group.


Asunto(s)
Anticoagulantes/efectos adversos , Factores de Coagulación Sanguínea/uso terapéutico , Transfusión Sanguínea , Hemorragia Gastrointestinal/inducido químicamente , Plasma , Warfarina/efectos adversos , Adulto , Anciano , Anciano de 80 o más Años , Transfusión Sanguínea/métodos , Servicio de Urgencia en Hospital , Femenino , Hemorragia Gastrointestinal/tratamiento farmacológico , Hemorragia Gastrointestinal/terapia , Humanos , Relación Normalizada Internacional , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Resultado del Tratamiento
7.
World J Gastroenterol ; 19(38): 6447-52, 2013 Oct 14.
Artículo en Inglés | MEDLINE | ID: mdl-24151363

RESUMEN

AIM: To study a retrospective analysis of patients who presented to the emergency departments (ED) with complaints related to foreign body ingestions. METHODS: Patients older than 16 years of age who presented to the ED between January 1(st) and December 31(st) of 2010 with complaints related to swallowed foreign bodies were identified from electronic health records and patient charts. RESULTS: A total of 100 patients presented with a complaint of foreign body ingestion during the study period. Overall, an X-ray was performed on 75 patients, and a fiberoptic evaluation was performed on 45 patients. A foreign body was detected in 46 (46%) patients. The diagnostic yield of the X-ray was 27 (36%) out of 75 patients, while the diagnostic yield of the fiberoptic evaluations was 21 (47%) out of 45 patients. The detected foreign bodies were mostly located in the esophagus (17 out of 46 foreign bodies detected). When the types of ingested foreign bodies were evaluated, 52 (52%) patients reported ingesting food, and 19 (19%) patients reported swallowing pins. An X-ray was performed on 33 patients with accidental food ingestions but yielded a positive result in only two cases. In 12 out of 21 patients with accidental food ingestion who underwent fiberoptic evaluation, the foreign material was detected and removed. CONCLUSION: Plain radiography is helpful in the localization of radiopaque swollen foreign bodies, while fiberoptic methods are useful as both diagnostic and therapeutic tools, regardless of radiopacity.


Asunto(s)
Deglución , Servicio de Urgencia en Hospital , Tecnología de Fibra Óptica , Cuerpos Extraños/diagnóstico , Admisión del Paciente , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Femenino , Cuerpos Extraños/diagnóstico por imagen , Cuerpos Extraños/fisiopatología , Cuerpos Extraños/terapia , Humanos , Masculino , Persona de Mediana Edad , Valor Predictivo de las Pruebas , Pronóstico , Radiografía , Estudios Retrospectivos , Adulto Joven
8.
Ulus Travma Acil Cerrahi Derg ; 19(3): 205-14, 2013 May.
Artículo en Inglés | MEDLINE | ID: mdl-23720106

RESUMEN

BACKGROUND: To compare ESI Five-Level Triage System with 5-Level Hacettepe Emergency Triage System (HETS), which was developed for Overcrowded EDs in our country. METHODS: Over a period of six days, patients were assessed by a different ED staff everyday using HETS, then re-evaluated blindly by an emergency physician using HETS. Then patients were evaluated blindly for a third time by an independent, ESI-using emergency physician. RESULTS: Of the patients in the study, 133 were men, 175 were women and the average age was 44.41±18.033. Inter-rater agreement was 97.40% (Kappa=0.963) between HETS and HETS-Blind, 74.35% (Kappa=0.646) between HETS and ESI-Blind, 74.67% (Kappa=0.652) between HETS-Blind and ESI-Blind. Inter-observer agreement between the second emergency physician performing HETS-Blind and the first emergency physician, resident, or nurse was very good (Kappa=1.0). Intern doctor, non-medical secretary and paramedic were found to have almost very good agreement (Kappa=0.971; 0.935; 0.864, respectively). An overtriage of 7.25% and undertriage of 1.08% were found in HETS. CONCLUSION: Complaint-based HEST developed for overcrowded Eds is a triage system with a very good agreement between observations and observers. Low undertriage and overtriage ratios, and easy application by all staff from a non-medical secretary to the emergency physician.


Asunto(s)
Aglomeración , Servicio de Urgencia en Hospital/organización & administración , Triaje/métodos , Adulto , Servicio de Urgencia en Hospital/normas , Femenino , Humanos , Masculino , Persona de Mediana Edad , Reproducibilidad de los Resultados , Índice de Severidad de la Enfermedad , Triaje/normas , Turquía
9.
Intern Med ; 47(24): 2117-20, 2008.
Artículo en Inglés | MEDLINE | ID: mdl-19075535

RESUMEN

OBJECTIVE: Smoking is an important risk factor in the development of community-acquired pneumonia (CAP). This study was designed to investigate the relationship between nicotine dependence level and the development of CAP. MATERIALS AND METHODS: The Fagerstrom test for nicotine dependence (FTND) was performed to measure nicotine dependence level (NDL). Subjects with a Fagerstrom score (FS) of 5 or lower were defined as low dependence level and a FS score of 6 or higher was defined as high dependence level. RESULTS: The risk of pneumonia development was higher in smokers than in nonsmokers (OR=2.19, 95% CI 1.13-4.23). The pneumonia development risk was 1.91 times higher in the low dependence level group compared to nonsmokers (OR=1.91, 95% CI 0.95-3.83). In the high nicotine dependence level group pneumonia risk was 2.93 times higher than in nonsmokers (OR=2.93, 95% CI 1.34-6.36). We also studied the relationship between CAP and the time to the first cigarette of the day. Risk was the lowest in the smoker group of after 60 minutes and risk ratios increased with decreased time. CONCLUSION: In this study, a high nicotine dependence level was found to be a risk factor associated with smoking for CAP development. The time period of the first cigarette after waking up is also important in pneumonia development as well as in the nicotine dependence level.


Asunto(s)
Personal Militar , Neumonía/epidemiología , Tabaquismo/epidemiología , Estudios de Casos y Controles , Infecciones Comunitarias Adquiridas/epidemiología , Infecciones Comunitarias Adquiridas/etiología , Humanos , Masculino , Neumonía/etiología , Factores de Riesgo , Fumar/efectos adversos , Fumar/epidemiología , Tabaquismo/complicaciones , Turquía/epidemiología , Adulto Joven
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA
...